OpenAI needs to raise at least $207B by 2030 so it can continue to lose money
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There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests
Of the 308 who benefited from tirzepatide, 254 (82 percent) regained at least 25 percent of the weight they had lost on the drug by week 88. Further, 177 (57 percent) regained at least 50 percent, and 74 (24 percent) regained at least 75 percent. Generally, the more weight people regained, the more their cardiovascular […]
Voyager 1 Is About to Reach One Light-Day from Earth
After nearly 50 years in space, NASA’s Voyager 1 is about to hit a historic milestone. By November 15, 2026, it will be 16.1 billion miles (25.9 billion km) away, meaning a radio signal will take a full 24 hours—a full light-day—to reach it. For context, a light-year is the distance light travels in a […]
Memories of .us
2025-11-11 How much do you remember from elementary school? I remember vinyl tile floors, the playground, the teacher sentencing me to standing in the hallway. I had a teacher who was a chess fanatic; he painted a huge chess board in the paved schoolyard and got someone to fabricate big wooden chess pieces. It was […]
Post-mortem of Shai-Hulud attack on November 24th, 2025
At 4:11 AM UTC on November 24th, a number of our SDKs and other packages were compromised, with a malicious self-replicating worm – Shai-Hulud 2.0. New versions were published to npm, which contained a preinstall script that: Scanned the environment the install script was running in for credentials of any kind using Trufflehog, an open-source […]
The HTTP Query Method
The following examples show requests on a JSON-shaped ([RFC8259]) database of RFC errata.¶ The request below uses XSLT to extract errata information summarized per year and the defined errata types.¶ QUERY /errata.json HTTP/1.1 Host: example.org Content-Type: application/xslt+xml Accept: application/xml, text/csv errata_status_code submit_date year, total, rejected, verified, hdu, reported ¶ HTTP/1.1 200 OK Content-Type: text/csv […]
I don’t care how well your “AI” works
I don’t care how well your “AI” works November 25, 2025 The other day I was sitting on the doorstep of a hackerspace, eating a falafel sandwich while listening to the conversation inside. The topic shifted to the use of “AI” for everyday tasks, people casually started elaborating on how they use “chat assistants” to […]
A cell so minimal that it challenges definitions of life
Life’s fundamental structure is the cell, and so the main things that a cell does — processing biomolecules, growing, replicating its genetic material and producing a new body — are considered hallmarks of life. But earlier this year, scientists discovered a cell so severely stripped of essential functions that it challenges biologists’ definitions of what […]
Statistical Process Control in Python
Figure 2.1: Statistical Process Control! In this workshop, we will learn how to perform statistical process control in Python, using statistical tools and plotnine visualizations! Statistical Process Control refers to using statistics to (1) measure variation in product quality over time and (2) identify benchmarks to know when intervention is needed. Let’s get started! Getting […]
Show HN: Real-time system that tracks how news spreads across 200k websites
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